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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-204
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples, normal retinas; RB cell lines Y79, WERI-RB1 and SO‐RB50; RPE cell line ARPE‐19
Methods transfection, luciferase reporter assay, CCK‐8 assay, transwell assay, annexin V‐FITC/PI staining, RNA immunoprecipitation (RIP), xenograft, qPCR, Western blot
Expression pattern down-regulated
Functional description NEAT1 promotes the development of RB via miR-204/CXCR4 axis. miR-204 expression was decreased in RB tissues and cells.
PubMed ID 30479013
Year 2019
Title Long noncoding RNA NEAT1 promotes the growth of human retinoblastoma cells via regulation of miR-204/CXCR4 axis.
Drug-related ncRNA NO

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